Here's how Sildalist Strong 140 mg works:
Dual PDE5 Inhibition:
Sildenafil and sildalist strong 140 are both PDE5 inhibitors. The enzyme PDE5 regulates the breakdown of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the penile blood vessels. Inhibition of PDE5 leads to an increase in cGMP levels.
Increased cGMP Levels:
Elevated levels of cGMP contribute to the relaxation of smooth muscles in the penile blood vessels. This relaxation allows for increased blood flow to the erectile tissue of the penis.
Enhanced Blood Flow:
Improved blood flow to the penis results in the dilation of blood vessels and increased engorgement of the erectile tissue. This physiological response helps men achieve and maintain an erection when sexually aroused.
Extended Duration of Action:
Tadalafil has a longer duration of action compared to sildenafil. While sildenafil's effects typically last for about 4 to 6 hours, tadalafil can provide efficacy for up to 36 hours. This longer duration allows for a more extended time frame during which sexual activity can occur.